 |
|
|
|
|
|
|
|
| Glucosamine (GS) has been used for the treatment and prevention of osteoarthritis, by itself or in combination with chondroitin sulfate (CS). Osteoarthritis is a major cause of disability among the elderly. Osteoarthritis is an age-related disease of joint cartilage, which results from structural change of the joints. |
|
| GS is an amino monosaccharide found in most tissues in the body. |
|
| GS is involved in the biosynthesis of glycosaminoglycans and proteoglycans, essential for the extracellular matrix of connective tissues. |
|
| Glucosamine is synthesized in chondrocytes in the body from glucose and glutamine. |
|
| The sources of glucosamine are natural (marine exoskeletons) and synthetic. |
|
|
|
| Glucosamine is found in hyaluronic acid, an essential component of extracellular matrix of connective tissue and chitin. |
|
| Glucosamine enhances proteoglycan synthesis, a fundamental component found in articular cartilage. |
|
| Glucosamine inhibits the cartilage-destructive enzyme collagenase. |
|
| Glucosamine has anti-inflammatory and antioxidant actions. |
|
| Glucosamine blocks the generation of superoxide free radicals by macrophages |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
| For additional remedies search the VHU database: |
|
|
|
|
| The Vitamin Herb University (VHU) provides health care professionals with superior science-based education on dietary supplements. |
|
|
|
|
