ADDITIONAL STUDIES
Glucosamine
Bourgeois P, et al.
Symptom modification by glucosamine sulfate in knee osteoarthritis: a randomized placebo and reference controlled double blind clinical trial.
Unpublished manuscript. 1999.
Braham R, et al.
The effect of glucosamine supplementation on people experiencing regular knee pain.
Br J Sports Med. 2003 Feb;37(1):45-9;
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Bruyere O, et al.
Glucosamine sulfate reduces osteoarthritis progression in postmenopausal women with knee osteoarthritis: evidence from two 3-year studies.
Menopause. 2004 Mar-Apr;11(2):138-43.
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Christgau S, et al.
Osteoarthritic patients with high cartilage turnover show increased responsiveness to the cartilage protecting effects of glucosamine sulphate.
Clin Exp Rheumatol. 2004 Jan-Feb;22(1):36-42.
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Cibere J, et al.
Randomized, double-blind, placebo-controlled glucosamine discontinuation trial in knee osteoarthritis.
Arthritis Rheum. 2004 Oct 15;51(5):738-45.
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Conrozier T.
Anti-arthrosis treatments: efficacy and tolerance of chondroitin sulfates (CS 4&6).
Presse Med 1998;27:1862-65.
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Crolle G, et al.
Glucosamine sulphate for the management of arthrosis: a controlled clinical investigation.
Curr Med Res Opin. 1980;7(2):104-9.
D'Ambrosio E, et al.
Glucosamine sulphate: a controlled clinical investigation in arthrosis.
Pharmatherapeutica. 1981;2(8):504-8.
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Drovanti A, et al.
Therapeutic activity of oral glucosamine sulfate in osteoarthrosis: a placebo-controlled double-blind investigation.
Clin Ther. 1980;3(4):260-72.
Forster K, et al.
Longer-term treatment of mild-to-moderate osteoarthritis of the knee with glucosamine sulfate.
Euro J Clin Pharm 1996;50:542(abstract).
Giordano N, et al.
Efficacy and safety of glucosamine sulfate in the treatment of gonarthritis.
Clinica Therapeutics 1996;147:99-115.
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Hehne HJ, et al.
[Therapy of gonarthrosis using chondroprotective substances. Prospective comparative study of glucosamine sulphate and glycosaminoglycan polysulphate]
Fortschr Med. 1984 Jun 28;102(24):676-82. German.
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Kerzberg EM, et al.
Combination of glycosaminoglycans and acetylsalicylic acid in knee osteoarthritis.
Scand J Rheumatol 1987;16:377-80.
Lopes Vaz A.
Double-blind clinical evaluation of the relative efficacy of ibuprofen and glucosamine sulphate in the management of osteoarthrosis of the knee in out-patients.
Curr Med Res Opin. 1982;8(3):145-9.
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Muller-Fassbender H, et al.
Glucosamine sulfate compared to ibuprofen in osteoarthritis of the knee.
Osteoarthritis Cartilage. 1994 Mar;2(1):61-9.
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Mund-Hoym WD.
Conservative treatment of vertebral osteoarthritis with glucosamine sulfate.
Therapiewoche 1980;30:5922-28.
Noack W, et al.
Glucosamine sulfate in osteoarthritis of the knee.
Osteoarthritis Cartilage. 1994 Mar;2(1):51-9.
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Nowlan C, et al.
Short report: ibuprofen versus glucosamine sulfate. Treating osteoarthritis pain.
Can Fam Physician. 2003 Dec;49:1632-4.
Pavelka K, et al.
Glucosamine sulfate use and delay of progression of knee osteoarthritis: a 3-year, randomized, placebo-controlled, double-blind study.
Arch Intern Med. 2002 Oct 14;162(18):2113-23.
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Pujalte JM, et al.
Double-blind clinical evaluation of oral glucosamine sulphate in the basic treatment of osteoarthrosis.
Curr Med Res Opin. 1980;7(2):110-14.
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Qui GX, et al.
Efficacy and safety of glucosamine sulfate versus ibuprofen in patients with knee osteoarthritis.
Arzneimittelforschung. 1998 May;48(5):469-74.
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Reginster JY, et al.
Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial.
Lancet. 2001 Jan 27;357(9252):251-6.
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Reichelt A, et al.
Efficacy and safety of intramuscular glucosamine sulfate in osteoarthritis of the knee. A randomised, placebo-controlled, double-blind study.
Arzneimittelforschung. 1994 Jan;44(1):75-80.
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Rovati LC.
The clinical profile of glucosamine sulfate as a selective symptom modifying drug in osteoarthritis: current data and perspectives.
Osteoarthritis Cartilage 1997;5:72.
Rovati LC.
Clinical research in osteoarthritis design and result of short-term and long-term trials with disease-modifying agents.
Intl J Tissue Reactions 1992;14:243-51.
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Rovetta G.
Galactosaminoglycuronoglycan sulfate (matrix) in therapy of tibiofibular osteoarthritis of the knee.
Drugs Exp Clin Res 1991;17:53-57.
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Tannis AJ, et al.
Effect of glucosamine supplementation on fasting and non-fasting plasma glucose and serum insulin concentrations in healthy individuals.
Osteoarthritis Cartilage. 2004 Jun;12(6):506-11.
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Tapadinhas MJ, et al.
Oral glucosamine sulphate in the management of arthrosis: report of a multicentre open investigation in Portugal.
Pharmacotherapeutica 1982;3:157-68.
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Thie NM, et al.
Evaluation of glucosamine sulfate compared to ibuprofen for the treatment of temporomandibular joint osteoarthritis: a randomized double blind controlled 3 month clinical trial.
J Rheumatol. 2001 Jun;28(6):1347-55.
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Vajaradul Y.
Double-blind clinical evaluation of intra-articular glucosamine in outpatients with gonarthrosis.
Clin Ther. 1981;3(5):336-43.
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Vajranetra P.
Clinical trial of glucosamine compounds for osteoarthrosis of knee joints.
J Med Assoc Thai. 1984 Jul;67(7):409-18.
Vas AL.
Double-blind clinical evidence of the relative efficacy of ibuprofen and glucosamine sulphate in the management of osteoporosis of the knee in out-patients.
Current Med Research Opinions 1982;8:145-49.
Verbruggen G, et al.
Systems to assess the progression of finger joint osteoarthritis and the effects of disease modifying osteoarthritis drugs.
Clin Rheumatol. 2002 Jun;21(3):231-43.
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by David A. Mark, Ph.D.
David A. Mark, Ph.D. is President of dmark consulting LLC, a firm specializing in research management services for the functional food, food ingredient, dietary supplement and performance nutrition industries.

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